ABSTRACT
Rhinoviruses and coronaviruses cause significant morbidity in immunocompetent people
of all ages and in patients with underlying chronic medical or immunosuppressed conditions.
Newer diagnostic tests, such as polymerase chain reaction (PCR), have expanded our
understanding of these respiratory viruses in clinical infections. These sensitive
diagnostic tests have been used to describe new members of these virus families, such
as human rhinovirus C (HRVC) and human coronavirus NL-63 (HCoV-NL63). The epidemiology
of these newly described viruses will help us develop better intervention strategies.
KEYWORDS
Rhinovirus - coronavirus - asthma - COPD - otitis media - sinusitis - croup
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Stephen B GreenbergM.D.
Department of Medicine, Baylor College of Medicine, One Baylor Plaza
BCM 104, Houston, TX 77030
Email: stepheng@bcm.edu
